Repeated (Recurrent) Miscarriages and Further Investigation

Repeated Miscarriages are one of the most disappointing experiences a couple can have when trying for a baby. In most cases, especially if the miscarriages occur during a natural pregnancy, patients may believe that this is a normal phenomenon and they should keep trying. We have treated many patients who had experienced more than 10 miscarriages when trying for a baby without receiving proper support or information from their health care provider.

Repeated miscarriages can be labeled as such if the patient has had three or more consecutive miscarriages. Having had only one miscarriage will not call for additional testing and investigation as that is something a large number of women experience at one point during their lifetime and it has been shown that women who have a single miscarriage will go on to have a healthy full-term pregnancy afterwards. However, if the patient keeps having miscarriages one after another, there is usually a medical condition behind it which needs to be investigated.

One of the first things that needs to be established is when the patient is experiencing her miscarriages. Certain times of gestation may point to different underlying causes behind the patient's miscarriages. If the patient has experienced her pregnancy losses after 12 weeks of gestation, then there is a high likelihood of cervical incompetence as the underlying cause. Cervical incompetence can be diagnosed through testing when the patient is not pregnant or via close monitoring during pregnancy.

When the patient experiences her miscarriages earlier on, during the first trimester, then other possible problems are accentuated. For instance, genetic problems with gametes (sex cells) could be one problem. Also, the couple may have chromosomal problems that show no symptoms but cause problems during reproduction (such as reciprocal translocations). Alternatively, thrombophilic defects that cause clotting problems are one of the main factors behind first trimester pregnancy losses.

A number of precautionary measures can be taken prior to or during your pregnancy in order to minimize the risk of yet another miscarriage. However, the underlying reasons must be well investigated and understood so that appropriate measures can be taken. For more information, please visit our website.

North Cyprus IVF Center - Gender (Sex) Selection Program

Because of some family balancing purposes or in order to prevent some sex-related genetic diseases, some couples would like to select the sex of their unborn child. At NorthCyprus IVF Center, we can legally offer the opportunity of gender selection treatment to such couples.
Identification of the right treatment method for gender selection depends on some below mentioned factors;

1) Age of the female patient: Based on the fact that, with age the ovarian reserves tend to diminish while genetic problems become more common, the age of the female partner is very important.

2) Semen analysis results for the male patient: MicroSort is one of a number of gender selection alternatives offered at North Cyprus IVF Center. Simply put, it is a sperm sorting technology that can be used for patients whose sperm concentration is more than 70 million/ml.

3) Hormone levels for the female patient: As they reflect the level of ovarian reserves and the quality of oocytes in the reserves, this piece of information helps us to get a more effective assessment of your needs and requirements to provide best suitable method of treatment.

Based on aforementioned results, we will be able to identify the right mode of treatment that best suits you. If you need any further assistance on tests and interpretation, please visit our "Male and Female Testing" section. Similarly, you may find answers to many questions about our gender selection program in the "Frequently Asked Gender Selection Questions" section.

We offer Gender Selection in 4 alternative methods at North Cyprus IVF Center;

1) MicroSort IUI for Gender Selection
This method is mostly suitable for fertile couples in their 20s because, a well inacted ovarian reserve, as well as a satisfactory sperm count, concentration, motility and morphology is required. This method is performed very similar to regular IUI. The female patient is expected to produce multiple oocytes through a very mild stimulation medication in order to increase the chances of pregnancy at the time of insemination. Subsequently, the MicroSorted sperm is injected intra-uterine. While MicroSort for gender selection with IUI treatment has 75% accuracy for gender selection for a boy, it has a 90% accuracy for gender selection for a girl.

2) MicroSort IVF for Gender Selection
Just like regular IVF-ICSI treatment, in this method the male partner’s sperm is sorted into X and Y bearing cells. The difference is that the female partner’s eggs are taken out and the sperm is injected directly into the nucleus of the egg for fertilization in the lab environment. Even thought the accuracy rates are very similar to the previously mentioned method, pregnancy rates are higher because of the fact that IVF procedures allow for multiple eggs to be fertilized and transferred back into the uterus.

3) IVF with PGD for Gender Selection
Even though it is a bit more expensive, this method not only allows us to identify the gender with 99.9%, but also gives us the chance of screening for most common genetic disorders. It is more suitable for females within the 20-35 age group and works just like regular IVF. The difference is that, a biopsy is performed once the embryos reach the 8-cell growth stage. It allows us to test for certain genetic conditions and determine the sex. Indeed, chromosomes X, Y, 13, 18 and 21, that are considered as the causes of almost 90% of all genetic-linked abnormalities are observed through this biopsy.

4) MicroSort IVF with PGD for Gender Selection
Combination of MicroSort and PGD is the best existing gender selection method offered by our clinic, especially for patients older than 35 years of age. This method combines the advantages of MicroSort and PGD technologies. While MicroSorting makes sure that majority of the sperm is sorted into the cells, PGD provides increased accuracy for gender selection and allows us to screen embryos for majority of genetic diseases.

For any more details on MicroSort, please feel free to visit our  "MicroSort Facts and Guidelines" section.

Source : http://goo.gl/yklXwA


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Tandem IVF Cycle

Tandem IVF Cycle has gained enormous popularity especially within the last few years. This distinct method of treatment offers women with low ovarian reserves and low oocyte quality, a chance of pregnancy with their own eggs, while at the same time having a back-up plan of egg reserves through egg donation. However, having regular menstrual cycles as well as active ovulation is a must to be considered for a Tandem IVF Cycle. In case the patient’s own eggs are not effective enough for pregnancy, Tandem IVF Cycle uses young and fertility proven donor eggs. Moreover, throughout this cycle, patient receives a considerably lower dose of medication because of the fact that she will be in need of only a few good quality eggs.

This is a great opportunity for women in their late 30's with high FSH levels. It can be interpreted as an investment in two different stocks to minimize the risk of a failed attempt. Similarly, it gives you the opportunity to make a choice of using your own eggs first and freeze donor's eggs for a potential future cycle and therefore, avoid the cost of two separate cycles. Thanks to the fact that we are legally capable to transfer up to three embryos in a given cycle, you will also be able to decide how many of your own embryos and how many embryos of donor eggs you would like to have transferred.

In case you have any further assistance on our tandem cycle IVF procedure or any question in general, please feel free to contact us.

Source : http://goo.gl/kob81U


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IVF Treatment with Cytoplasmic Transfer

Cytoplasmic transfer is not a method of treatment on its own. Indeed it is a procedure used with IVF/ICSI Treatment. As one of the latest innovations in IVF Treatment, it was created mainly to help women who experience infertility because of deficient or damaged mitochondria which is contained within an egg's cytoplasm. Mitochondria provides the necessary energy for cell growth as well as efficient cell division. Therefore a deficiency in mitochondria will prevent successful cell growth and cell division. Consequently, it may cause recurrent implantation failures, high levels of embryo fragmentation, poor embryo quality and development, and last but not least a failed IVF.

The main difference of IVF/ICSI involving a cytoplasmic transfer and a regular IVF/ICSI is that, the former uses not only the patient's own eggs but also donor eggs in order to obtain healthy mitochondria from young and healthy donor eggs. Healthy mitochondria will aid rejuvenate the patient's eggs and thus, maximize the chances of success.

As North Cyprus IVF, we have been offering Cytoplasmic Transfer to our patients since 2012. Even though we do not have sufficient numbers to publish significant statistics, it would be fair to mention that cytoplasmic transfer potentially adds a few percentages to the chances of success for women in their early 40s. Still, please note that; cytoplasmic transfer cannot correct any genetic defects related with the egg that may have caused by older age. We recommend this procedure to patients in their mid 40's. However, given the fact that possibilities of success with own eggs declines considerably after mid 40s, we also recommend Donor Egg IVF treatment especially after a certain age.

At North Cyprus IVF, we are proud to guarantee high quality treatment with maximum service quality standards at affordable low cost. For any further assistance or for a quote, please do not hesitate to send us a message by filling out our contact form.


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Minimal Stimulation IVF - (Mini IVF) Treatment

Mini IVF is very similar to typical IVF in terms of procedures used during treatment. The main difference is that; while typical IVF aims to produce a certain amount off eggs for retrieval, mini IVF aims to produce only a few eggs of higher quality. In other words, mini IVF is performed to get a low count but higher quality of eggs through comparatively  weaker and/or lower doses of medications.

At North Cyprus IVF Centre this option of treatment is generally offered to patients; in their late 30s or early 40s who do not respond well to IVF stimulation protocols, has diminished ovarian reserves, are not willing to use high dose of IVF stimulation medication, whose oocyte quality has been compromised and FSH levels are high.

By the way, it should be noted that when women reach at a certain age, they face with depleted ovarian reserves as well as compromised quality. Therefore, given the fact that Mini IVF will only help to get slightly higher quality eggs, North Cyprus IVF center also recommends "IVF with Egg Donation" as a treatment option if getting a successful outcome is more important than using your own eggs.

If you need any further assistance, please feel free to get in touch with us.

Source : http://goo.gl/MkdqWU


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In-Vitro Fertilization (IVF) with ICSI

In Vitro Fertilization (IVF) is the process by which an egg is fertilised by sperm outside the body. Subsequently, the embryos considered to be the best are placed into the woman’s womb with the use of a plastic catheter.

At North Cyprus IVF, this process is followed through five basic steps;

1) Fertility testing and identifying the right type of treatment as well as the precise dose of medication.
2) Hormone supplements and stimulation of healthy egg(s) in the ovaries.
3) Collecting the eggs.
4) ICSI (Intracytoplasmic Sperm Injection); Combining the eggs and sperm in the laboratory for fertilization and embryo growth.
5) Embryo Transfer.

At North Cyprus IVF, we guarantee the highest quality treatment with the best quality standards at low cost.

For any more information including cost of our IVF ICSI treatment and medical details, please do not hesitate to contact us.

Source : http://goo.gl/kyMexH

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Defining Infertility

We can simply define Infertility as "inability to conceive" or "inability to carry pregnancy to a full-term". Close to ten percent of the western population, those between the ages of 15-44, having infertility problems. Although many assume infertility is female problem, female and male infertility have almost the same level of prevalence within the society.

While primary infertility definition includes couples who have been trying to get pregnant for the last year but incapable to do so, secondary infertility involves couples who have previously conceived but are not able to do so any more. Some factors that may cause secondary infertility are ; age, premature menopause, exposure to radiation therapy, chemotherapy, surgical complications, bad diet and more.

Initial fertility testing differ for each couple depending on the factors such as; time they have been trying to conceive, their age, personal history of fertility treatments, medication protocols used in these treatments, their history with miscarriages and many more.

Please, keep in mind that there is no universal infertility treatment that can be applied each and every patient. Treatments are customized and the one you need cannot be identified until you have been thoroughly checked and tested.

Below, you may find links that will direct you to our pages where you can find detailed information. If you need any more assistance please, feel free to contact us.

Source : http://www.lowcostivf.net/infertility.htm#.U5V-pZSSzM4

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Treatment Options

Going through a complete assessment of your personal fertility has a great importance on choosing the right treatment option since each treatment is suitable for a specific patient group regarding their fertility requirements.

Initial testing process is the first step infertility assessment. Detailed information where we describe some basics can be found in our "Infertility Testing and Interpretation of Test Results" section. Next, on the ; "Choosing the Right Treatment" section, you can come across some treatment suitable to some patient groups regarding factors such as; age, fertility assessment, previous obstetric history as well as history of fertility.

Together with the treatment, patient's lifestyle has also a great effect on the outcome of the treatment. Therefore, please do not forget to check our "Boost your Fertility".

Deciding on the clinic for your treatment might be challenging for you as you may have many choices around. However, be aware not to choose a clinic that is willing to proceed any treatment without a thorough evaluation of your personal needs. Please note that IVF is a personal, unique treatment and there isn't a single prescription applicable for everyone.

Some treatment options offered by the North Cyprus IVF Clinic is listed below. For more information, please do not hesitate to get in touch with us. We will be more than happy to assist you.

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North Cyprus IVF Centre

Life is nothing but the results of our choices. However, making the right choice depends on the information we acquire on our options. Thus, we want to inform you about numerous specific services presented at the North Cyprus IVF Clinic.

North Cyprus IVF was not only the first IVF clinic set up on the island but also the very first clinic to introduce egg and sperm donation programs as well as gender selection for family balancing. As the first ISO 9000 qualified clinic in Northern Cyprus, North Cyprus IVF has kept its leading role since 1998. Currently, we are proud to be the only clinic in the North with the ability to perform all the genetic testing and screening in house with no need of third party laboratories assistance.


North Cyprus IVF collaborates with many prestigious hospitals, scientists and agencies all around the world. Consequently, MicroSort ® technologies was brought to Cyprus in 2011.nIn fact, with the exception of America, our clinic is the very only patented clinic with this option all around the world.

Dr. Savas Ozyigit who has many publications including the chapter of "Egg Donation" in the first IVF textbook published in Turkey, is our award winning director with memberships of American Society of Reproductive Medicine and the European Society for Human Reproduction and Embryology.

Source : http://www.lowcostivf.net/northcyprusivf.htm


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MALE INFERTILITY TESTING

In male infertility assessments, a semen analysis, ideally on the third or for day of abstinence (no sexual activity), is the first step. The capacity of the sperm to fertilize the egg is measured through a sperm sample which reveals parameters like; sperm count, concentration, motility, morphology, round cell count, pH and more. Without a doubt, some other tests might be required as well depending on patient's personal history of infertility, testing and or treatment

The WHO criteria for normal sperm values is listed as follows;

Volume: > 2.0 ml

Concentration: >20 million/ml

Motility: > 50%

Morphology: >30% with normal morphology

White Blood Cells (Round Cells): < 1 million/ml

pH: 7.2-7.8

Please feel free to contact us in case you need any further assistance. We will be glad to help. 

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Repeated IVF Failures & Further Investigation

Without a doubt, IVF failures are one of the most frustrating occasions for a couple throughout their IVF path. Especially when they aren't fully informed about the reasons behind a number of failed IVF attempts, it may even lead to depression.
North Cyprus IVF pays extreme attention on this issue. In case of a failed trial, our patients are subject to
go through a complete analysis before their next IVF attempt in order to rule out some known possibilities. Additionally, if consequent results are not satisfying enough, some other factors are considered and observed in detail.

Some of the exigent factors that cause for IVF implantation failure can be cited as follows;

Uterine Infection

It is highly believed that infection of the uterine cavity with bacteria may result in an inhospitable environment and therefore may cause a failure of embryos to implant. Similarly, some other infectious diseases such as; CMV, IgG, Chlamydia etc. should be examined within this framework. Generally, antibiotics are used for infection treatments.

Immune factors

In some circumstances, the immune system is suspected to perceive the embryo as a foreign entity. Hence, it rejects the implantation of embryos.

Thrombophilias

Based on large scale investigations and researches, the existence of thrombophilias in women is associated with the risk of miscarriage. Furthermore, some researches even indicate the relation between thrombophilias and implant failures.

Although these factors can not be presented as a complete list of causes behind IVF failures, they are accepted as main contributors. However, for a much better personal assessment some specific analysis are needed to be performed with all aspects and conditions included.


If you have any specific questions or answers regarding the type of procedure you are interested in, please, do not forget to check our "Frequently Asked Questions" section. And please, do not hesitate to use our contact form for any more information.

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Our newest twins!

Enclosed is a photo of A. and L.. The clinic is welcome to use it. I had a difficult pregnancy and traumatic delivery but we all made it. After everything I went though, it was a success.  Please let Dr. Savas and everyone know at the clinic know how grateful we are. We are so happy. T. and I came to the clinic last summer & the procedure was done on July 1st.  I would love to write a testimony regarding all the positive things about the clinic, just guide me on the new website. Lots of Love to you and everyone at the clinic!

Z and T - United Kingdom


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Egg Donation at North Cyprus IVF

Egg Donation IVF is a method of treatment especially for women with conception failures based on deficient or unhealthy eggs. Women with below mentioned conditions are ideal candidates for this method of treatment;

- Women who are in premature menopause or menopausal
- Women who do not produce eggs
- Women who have damaged ovaries or hereditary malfunctioning ovaries.
- Women have have weak ovarian reserves
- Women who suffer from hereditary genetic disorders
- Women who have had a couple of miscarriages because of chromosomal abnormalities
- Women with a number of failed IVF trials with her own eggs.

Egg Donors at North Cyprus IVF?

International students in Cyprus between the ages of 20 and 24 constitute our main egg donor base at North Cyprus IVF. Each goes through a strict screening process and receives psychological counseling, a number of infectious disease testings and a karyotype analysis.

Main criteria that are considered during the egg donor selection are;
- women between the ages of 20 to 29
- women with BMI's between 19 to 24
- women with no hereditary genetic diseases in family.
- women who do not suffer from a mental disability
- women who do not use drugs and do not smoke

Our Egg Donation Program

Our egg donation program is almost the same as our 5-step IVF treatment program. The only difference is that, while the egg donor receives ovulation induction medication for ovarian stimulation, female partner gets oestrogen and progesterone supplements so that her uterus becomes ready for a successful implantation.

http://www.gender-selection-ivf.co.uk/Egg_Donation_north_cyprus.html


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IVF with ICSI at North Cyprus IVF Clinic

The process of In Vitro Fertilization (IVF)  treatment can be simply described as the combination off eggs with sperm in the laboratory environment. As a basic part of this procedure ICSI Is performed so that the best quality sperm is selected and injected into the nucleus of the egg for fertilization. As a result, we catch the opportunity to get potentially the highest quality embryos.

At North Cyprus IVF, IVF treatment is performed through below mentioned five steps;

1st Step: Visiting your gynecologist for pre-testing and a sonogram.

2nd Step: Based on those results, a preliminary work and stimulation of the ovary.

3rd Step: Arriving Cyprus where a final sonogram is executed so that the patient is prepared for the trigger injection.

4th Step: Egg retrieval and in vitro fertilization.

5th Step: Transfer of the embryo transfer.

Our experts as well as IVF specialists at North Cyprus IVF are always more than happy to enlighten you with your IVF treatment options.

Source : http://www.gender-selection-ivf.co.uk/North_Cyprus_IVF_Treatment.html

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Intra-Uterine Insemination (IUI)

Intra-Uterine Insemination (IUI) is a non-invasive, as well as a low cost fertility treatment among many fertility treatment options offered at North Cyprus IVF.  The main purpose of this treatment is to catch a higher possibility of fertilization through increasing the number of sperms that reach the fallopian tubes.

Mostly, couples with below indicated conditions prefer IUI;

Low sperm count.
Decreased sperm mobility.
Requirement of donor sperm.
A hostile cervical cases such as cervical mucus being quite thick
Sexual dysfunction

Simply put, it is the placement of a number of washed sperm directly into the uterus with the use of a catheter. Lab processes a semen sample and dispatches the sperm from the seminal fluid while the development of follicles are observed through a number of sonograms. Once the follicles reach the ideal level of growth, human Chorionic Gonadotropin (hCG) is injected in order to stimulate the release of eggs from the follicles. After 35 hours of this injection, processed sperm is injected into the uterus with a catheter.

This treatment increases the number of sperm cells that are put in the uterus and therefore brings a higher probability of conception.

http://www.lowcostivf.net/intra-uterine-insemination-iui-treatment-north-cyprus-ivf.htm#.U32-5NoayK0

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Male Infertility - Causes and Investigation

Two main factors that affect infertility in men are either caused by problems making sperm or problems with the sperm's ability to reach the egg and fertilize it. In some cases, a man is born with the problems that affect his sperm. Other times, problems occur later in life because of illness or injury. Additionally some factors such as; alcohol, drugs, cigarette smoking, medicines, health problems may reduce sperm number and/or quality.

In order to understand the cause and severity of the problem, a semen analysis would show crucial parameters such as sperm volume and sperm count. However, having enough sperm cells is not sufficient. They also need to have a certain level of motility. Similarly, sperm morphology is another very important factor.

Sometimes, even if sperm production is not sufficient enough, minor surgical procedures like TESA and MESA can be used to retrieve sperm. In other cases where no sperm can be found or the quality is considerably low, donor sperm usage becomes the only alternative.

For more information please see IVF with Sperm Donation - http://goo.gl/DLRhel

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Female Infertility - Causes and Investigation

 Most common causes of infertility in women are; absence of ovulation or insufficient quality of the eggs (oocytes) for fertilization. Additionally, many factors such as; age, stress, excessive use of tobacco and alcohol, sexually transmitted and infectious diseases, being overweight or underweight, athletic training, lack of the essential nutrients resulting from a poor diet and any factors leading to hormonal imbalances may act on a woman's fertility.

Aging has a crucial effect on a woman's fertility. After the age of 30, a woman's chance of having a baby decrease expeditiously each year. Mainly because the health of a woman's ovaries to release eggs and health of the eggs declines whereas, risks of having a miscarriage, as well as risks arising from a woman's personal health problems which may interfere with fertility increases. Therefore women in their 30's who have been trying to get pregnant for six months or longer should immediately consult their doctors for a complete fertility evaluation. As for most healthy women under the age of 30, should not worry unless they have been trying for at least a year.

Infertility testing and evaluation starts at your gynecologist's, where a sonogram will be used to find out the number of potential eggs in each ovary on the 2nd or 3rd day of your menstrual period. Besides, hormone testing will be useful in order to make an evaluation of your ovarian function including FSH, LH, Estradiol, Prolactin, TSH and AMH. Depending on the results, the most appropriate course of action will be decided.

For more information please visit: http://www.lowcostivf.net/causes-of-female-infertility.htm#.U3BgHdoayK1

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Patient Testimonial

Amy was my initial co ordinator and she is excellent. She responded back to my queries very promptly and was always available if i needed to speak to her. On my arrival to Cyprus, the taxi driver was waiting and the check in at the Golden Tulip was very fast and stress free. I was also given a welcome pack from the clinic upon my arrival which had details of my appointment with the doctor the following day. ALL the staff at the clinic are excellent, very friendly and always willing to help. Melesse, Fatosh and Angie were excellent and very supportive through a very stressful and anxious time. Thank you. Idil and Dr Savas were also very excellent. They both explained everything very well and answered any questions which we had. Dr Savas made me feel re assured that everything would be ok as it is a very anxious time during treatment and there are always loads of questions which go around your mind. The centre itself is clean and welcoming and is located around the corner from Golden Tulip Hotel so is walking distance which was also a bonus. My experience with North Cyprus IVF was excellent..... waiting for the results.

R.K, United Kingdom

Via http://www.visitandcare.com/ivf/cyprus/nicosia/north-cyprus-ivf#reviews


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How to boost your fertility

Here are 6 tips on how to boost your fertility and chances of success with treatment :

1. Weight Management
2. Eat Right
3. Avoid Drugs, Cigarettes and Alcohol consumption
4. Avoid Stress
5. Have sex!
6. Make sure your partner stays healthy as well!

Please visit http://goo.gl/9BozgX for more information.


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Choosing the right treatment for you

Unless you have had a thorough infertility investigation to identify your reasons for infertility it could be difficult to choose the correct treatment.
Since each patient is unique, the same treatment will not fit everyone.

We suggest that the first step be to have the following hormone tests on days 2-3 of the menstrual cycle in order for us to interpret and prescribe the best course of treatment :

FSH
LH
E2
Prolactin
TSH
AMH

Please visit  http://goo.gl/rOV7cS for further information.

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Gender Selection at North Cyprus IVF

Here are the important factors to consider when deciding which Gender Selection method will give the highest success :
- Age of the female
- Semen analysis of the male
- Hormone results of female

Once we have further information, we can identify the best method of treatment specific for you.

Our treatment options include :
IUI with Microsort®
IVF with Microsort®
IVF with PGD
IVF with PGD and Microsort®

For more information please visit : http://goo.gl/KYHI63

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What is Infertility?

The inability to conceive or inability to carry pregnancy to full term can define Infertility.
Around 10% of women ages 15-44 in the Western population have difficulties getting pregnant or carrying to full term.

Each couple will need to undergo infertility investigation and this could vary depending on a few factors including : how long you have been trying to conceive, your previous history of fertility treatments, age, medication protocols used in previous treatment as well as the history of miscarriage or failed treatments.

It is our goal to ensure that each fertility treatment is unique and customized which is why we ask for all possible information before beginning your treatment.

For further information please visit : http://www.lowcostivf.net/infertility.htm

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Recommendation North Cyprus IVF

After our second visit in March 2014 to Northern Cyprus for our second attempt of IVF, our first IVF was with a different company in Cyprus

However, this IVF in March was outstanding cannot fault any of the staff, they were brilliant we were treated as individuals nothing was too much for the staff.

Their spoken English was brilliant including the Dr. Savas Ozyigit,   who tried to make me feel at ease in the Theatre on transfer day.

They have all been supportive, before and after transfer, sadly it failed but we will be back again to try, we felt like we were treated as people and not just a number like our first IVF try.

Our thanks go out to the Dr Ozyigit and  the theatre staff, and including Deedee for being there for my constant questions by email, and to Angie who nothing is and was too much for her, so thank you all, for your help and support.

I would like to say we met some wonderful people, and hope to keep in contact, see you soon for our next attempt.

Y & G, United Kingdom

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Success Rates 2013

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Sickle Cell Disease

Sickle cell anemia is caused by an abnormal type hemoglobin called hemoglobin S and is a case where the red blood cells are sickle shaped.

The job of these hemoglobin molecules is to bind and carry oxygen to the tissues but in the presence of abnormal hemoglobin molecules, this delivery is less optimal and can cause problems. 

HBB gene mutation is the cause for sickle cell disorder however with our PGD (Pre-Implantation Genetic Diagnosis) treatment you can prevent passing this gene onto your children. 

If you are at risk for passing sickle cell please visit the link below for further information about our PGD IVF treatment for genetic disorders. 

http://www.lowcostivf.net/sickle-cell-anemia-disease-prevention-treatment.htm#.U0BlnVG1Zck

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Azoospermia and Surgical Sperm Extraction Methods

One of the main factors of infertility is Azoospermia and has been estimated to effect 15% of all male infertility cases.

This factor which is in essence the complete absence of live sperm cells in the ejaculation can be split into two groups : obstructive azoospermia and non-obstructive azoospermia. The former suggests that there is a blockage along the sperm delivery system as where the latter suggests a problem in the production of sperm. 

The reasons behind this can be due to testicular failure but further investigation should be carried out by a urologist for a full diagnosis. 

We offer a few different options for treatment in such cases including : 

PESA - Percutaneous Epididymal Sperm Aspiration
MESA - Micro Epididymal Sperm Aspiration
TESE - Testicular Sperm Extraction

The diagram below shows how each of the surgical sperm retrieval methods are administered:

Please click on the link below for further detailed information
http://www.lowcostivf.net/tese-microtese-tesa-surgical-sperm-extraction.htm#.U0BlAlG1Zck


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Repeated (Recurrent) Miscarriages Further Investigation

Repeated (Recurrent) miscarriage is defined as the loss of three or more pregnancies. If you have experienced a single pregnancy loss, the odds are, you are not likely to have another miscarriage. However, if miscarriages are recurrent and are experienced in similar time frames of a pregnancy, further investigation will be needed. Recurrent miscarriages can have many possible causes. When a patient experiences several miscarriages, then it will make sense to get evaluated for the conditions below:

1- Genetic Factors
All couples with a history of recurrent miscarriage should have peripheral blood karyotyping performed. The finding of an abnormal parental karyotype will necessitate consultation with a geneticist. Certain genetic abnormalities can be screened for through PGD testing while others might require alternative avenues.

2- Cervical Weakness
This is a known anatomical cause of recurrent miscarriages. The cervix (or neck of the womb) is normally strong enough to remain closed throughout the course of pregnancy, in spite of the ever-increasing size and weight of its contents. In fact, it remains strong throughout pregnancy and near the time of labor, special hormones are released to make it softer so that it is dilated enough for a successful baby delivery. With an incompetent cervix, the cervix is anatomically weak, making it unable to carry the baby. Typically, miscarriage caused by an incompetent cervix occurs between sixteen and twenty-four weeks of gestation.

3- Endocrine Factors
The term endocrine hormonal factor in infertility refers mainly to the absence of ovulation, which results in disorders of the menstrual cycle (oligomenorrhoea, primary or secondary amenorrhea) and less commonly to the condition of luteinized unraptured follicle. In cases of oligomenorrhoea or amenorrhea satisfactory results can be achieved with conventional ovulation induction methods, avoiding the use of assisted conception techniques.

4- Immune Factors
These can include Antithyroid antibodies, Antiphospholipid syndrome, Alloimmune factors. There are tests that can be administered. In some cases, we find that suppressing your immune system response around the time of embryo transfer reduces the likelihood of an implantation failure and a very early miscarriage. 

5- Infective Agents
TORCH (toxoplasmosis, other [congenital syphilis and viruses], rubella, cytomegalovirus and herpes simplex virus) screening is unhelpful in the investigation of recurrent miscarriage. These infection diseases can cause implantation failures, therefore, IVF failures as well as pregnancy losses after implantation has occurred. Having tested for infectious diseases will rule out this possibility.

6- Inherited Thrombophilic Defects
Inherited thrombophilia defects, including activated protein C resistance (most commonly due to factor V Leiden gene mutation), deficiencies of protein C/S and antithrombin III, hyperhomocysteinaemia and prothrombin gene mutation, are established causes of systemic thrombosis. A thrombophilia gene panel needs to be evaluated to make a diagnosis.


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Where to have your Pre-testing

Below is a list of places where you can have your initial tests and scans before planning your treatment with North Cyprus IVF Centre:

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Quels tests avez-vous besoin pour le traitement?

Nous avons besoin d' une série de tests pour la fertilité évaluation / remise en forme pour la grossesse ainsi que le dépistage des maladies infectieuses . Chaque épreuve que nous commandons sert un but différent et chacun de ces essais aura une incidence sur votre traitement .

Pour l'évaluation de la fertilité , nous demander à chaque patiente d'avoir la suite du test effectué le jour 2 ou 3 jours de leur cycle menstruel : FSH , LH , Estradiol , prolactine , TSH et tests hormonaux AMH . Le test AMH est indépendant de votre cycle menstruel et peut être fait à tout moment , mais nos patients trouver plus facile d'avoir tous les tests effectués le même jour lors de leur visite à leur médecin . Il sera également important d'avoir une échographie pelvienne de la ligne de base au cours de cette visite pour la numération des follicules antraux dans les ovaires et vérifier qu'il n'y a pas de problèmes majeurs visibles dans l'utérus qui peuvent interférer avec une grossesse réussie .

Le patient de sexe masculin est nécessaire d'avoir une analyse du sperme fait . Surtout si il n'a pas eu un enfant dans le passé proche , il sera important d'observer les paramètres du sperme tels que nombre / volume / mobilité / morphologie / niveau de pH et le nombre de cellules rondes . Dans certains cas , une petite infection dans le sperme peut compromettre l'ensemble du processus , par conséquent, il est important d'être préparé pour les précautions possibles que nous pourrions avoir besoin de prendre .

Tous les patients qui suivent un traitement à notre pratique sont tenus de se soumettre au dépistage des maladies infectieuses . Cela inclut les patients qui subissent des traitements de donateurs ainsi . Il ya trois raisons principales pour le dépistage des maladies infectieuses :
1 - Pour protéger la propagation des maladies infectieuses dans notre laboratoire et pour éviter d'exposer d'autres patients à ces maladies .
2 - Pour éviter d'exposer les embryons à des maladies infectieuses qui pourraient venir de leurs parents .
3 - Pour protéger le personnel de laboratoire de l'exposition aux maladies infectieuses lors de la manipulation d'ovules et de sperme .
La validité des tests de maladies infectieuses est de six ( 6) mois . Tant que les patients ont leur test effectué dans le délai de 6 mois avant leur temps de traitement , nous n'avons pas besoin d' un test de répétition . Toutefois, si les patients n'ont pas les résultats des tests actuels , alors nous allons administrer ces tests ici à notre pratique avant de manipuler tous les échantillons .
Seuls les résultats des essais cliniques et des hôpitaux de renom seront acceptées, et les résultats des tests originaux devront être présentés au moment de votre première visite . Les photocopies et les pièces jointes numérisées ne sont acceptés comme preuve temporaire de test jusqu'à ce que nous voyons les originaux .
Les tests de maladies infectieuses exigés par notre pratique sont les suivants :
Pour patient: Anti- VIH , anti- VHC , AgHBs , VDRL , rubéole IgG , IgG anti-CMV , toxoplasmose et IgG
Pour les patients de sexe masculin : Anti- VIH , anti- VHC , AgHBs , VDRL .

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Quelle est la limite d'âge pour le traitement de la sélection du sexe ?

Il n'ya pas de limite d'âge pour le traitement de la sélection du sexe , mais il ya une limite d'âge pour le traitement de FIV . C'est par rapport à la façon dont vous êtes susceptible d' atteindre le succès . Si vous n'utilisez pas un donneur , que nous voulons vous assurer que vos oeufs sont viables et nous avons une chance de grossesse avec vos propres oeufs . C'est une des raisons pour lesquelles nous aimons Hasta qui ont subi une série de tests d'évaluation de leur taux de fécondité avant de procéder à un traitement . Basé sur les résultats de ces tests , nous sommes en mesure de former une opinion sur la façon dont nous sommes susceptibles d' obte c'est un bon compteur et la qualité des œufs dans un cycle de FIV et la probabilité thes oeufs sont de produire une grossesse saine. Nous essayons de souligner que plus de 35 ans , le niveau de fécondité pour les femmes Biol Hasta de refuser et qui affecte les chances de succès avec le traitement . Après l'âge de 40 ans, à moins que les taux de grossesse Hasta chuter de façon spectaculaire et avoir un niveau satisfaisant de profil hormonal qui les providesa avec quelque chance de succès , nous déconseillons de traitement avec les œufs.


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Boost your Fertility

Even though infertility may not be something that can be completely cured with what you eat or what you do, it may still be possible to boost your fertility and aid with your chances of success with natural conception or with infertility treatments. Since women are the ones to carry a pregnancy, they should be more careful about certain habits:

1- Weight Management: Watch your weight and make sure your BMI stays within a healthy range. Excess body fat is not only detrimental to your health, but can also trigger overproduction of certain hormones that can possibly disrupt ovulation. Similarly, being underweight result in underproduction of these hormones and your body may not produce enough of them for ovulation.

2- Eat Right: Make sure that you eat healthy and that you receive enough protein, iron, zinc, folic acid and Vitamin C. Deficiency in these nutrients have been associated with variations in menstrual cycles as well as miscarriages. Folic acid is especially important during pregnancy for the neural development of your baby. If your busy schedule does not allow you to measure precisely what nutrients are in your body, it will make sense to receive a daily tablet of "one a day" vitamins.

Another very important tip to know about boosting your fertility is eating more alkaline. The more acidic the body's environment, the more difficult it us for the sperm to complete its journey and reach the egg for fertilization. Sperm survival is dependent on the correct pH balance. Therefore, avoid foods and drinks that are too acidic and opt for a more alkaline diet.

3- Avoid drugs, cigarettes and excessive alcohol consumption. They are not only detrimental to your health, but toxins in cigarettes and drugs can damage your eggs, negatively affect the fertilization and implantation processes and can contribute to aging of your ovaries. Excessive alcohol consumption has been linked to altered levels of estrogen, which can cause implantation failures.

4- Avoid Stress: Clinical studies indicate that women under stress and psychological distress are less likely to conceive. There is no single prescription for stress management. You should do whatever works for you. Reading a book, yoga, meditation, short weekend getaways, writing your own book! are some examples.

5- Have sex! Regular intercourse have been shown to help with more predictable cycles and normal ovulation. Having intercourse at least once a week will help keep things in balance...

6- Make sure your partner stays healthy as well! The same things that can affect your fertility are likely to affect his fertility as well. Therefore, heavy smoking, excessive drinking anf eating unhealthy are never a good idea for anyone! It has been shown that receiving Vitamins C, E and Selenium are associated with production of healthier sperm. 

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Infertility Testing & Interpreting Test Results

Infertility testing can be very different for different patient groups. For instance, if you have been trying to conceive for some time without success and have had no prior testing and/or investigation done, then the starting point will be the following:

For female partner:

- A sonogram will need to be performed on day 2 or day 3 of her menstrual period. This sonogram will be indicative of the number of antral follicle count (potential eggs for ovulation) and it will give your gynecologist a chance to observe if there are any problems such as cysts in the ovaries, or polyps/fibroids in the uterus/cervix that can possibly interfere with a successful pregnancy process.

- On the very same day, FSH, LH, Estradiol, Prolactin, TSH and AMH hormone tests will need to be administered to make an assessment of the ovarian function. Each of these hormones reflect a different aspect of your fertility. Our specialists at North Cyprus IVF will evaluate your test results and provide a comprehensive feedback on your test results.

For male partner:

- A semen analysis will need to be performed according to WHO 2010 Criteria, as explained in the "Causes of Male Infertility" section.

For couples who have had their initial testing and perhaps have been through a round of fertility treatment will need further investigation. Based on the problems or the lack of problems that may have been observed in initial testing, the following will be investigated:

- A hysterosalpingography for a thorough investigation into the tubes and the uterus

- Infectious disease screening for both partners including Toxoplasmosis, CMV and Chlamydia for the female partner. Sometimes a small infection can cause your body to reject embryo implantation and therefore prevent you from getting pregnant. A short cure of antibiotherapy can sometimes be a solution to a long-suffered infertility problem.

- A karyotype analysis for chromosome testing. If one of the partners suffers from an abnormal karyotype, a genetic problem may be transferred to the offspring. The nature and the severity of the problem will be indicative of what types of measures should be taken.

For couples with repeated IVF failures and/or repeated miscarriages, in addition to the tests mentioned above, female thrombophilia testing will be in order including the following:

MTHFR C677T

MTHFR A1298C

Factor II

Factor V Leiden

PAI 1

Thrombophilia defects can potentially cause blood clotting problems, where blood clots can get into the placental circulation and stop your baby's heart, therefore, resulting in a miscarriage. Thrombophilia defects have also been identified with implantation failures.

This is not a comprehensive list of infertility testing and we may ask for different tests depending on your unique history of infertility.

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Pourquoi ai-je besoin d'utiliser des médicaments si je n'ai pas de problèmes de fertilité?

                                                      

C'est l'une des questions les plus fréquemment posées par les patients subissant un traitement pour la sélection du sexe . Étant donné que la plupart des patients ont besoin de la sélection du sexe pour leur deuxième ou troisième ou même quatrième grossesse , ils sont pour la plupart des individus fertiles qui sont en mesure d'obtenir une grossesse par des moyens naturels . Cela soulève la question de savoir pourquoi ils ont besoin d'utiliser des médicaments de fertilité comme les autres patients qui ne sont pas en mesure de concevoir naturellement . La réponse est simple . Que vous soyez en mesure de concevoir naturellement ou non , dans un traitement de FIV , nous aurons besoin d'obtenir plusieurs ovules , et donc plusieurs embryons afin que nous puissions maximiser vos chances de succès . Sans l'utilisation de médicaments de fertilité , les ovaires sont susceptibles de libérer un seul oeuf dans un cycle menstruel donné. Cet oeuf unique peut ou peut ne pas être d' une qualité optimale . Surtout dans les traitements de la sélection du sexe , nous avons besoin de plusieurs oeufs de sorte que nous pouvons avoir plusieurs embryons , ce qui nous permettra de trouver au moins un embryon qui est sain génétiquement et c'est du sexe désiré .

Pas tous les œufs engraisser dans des embryons de bonne qualité et ne sont pas tous les embryons fécondés vont survivre jusqu'à ce que le jour du transfert de l'embryon , et non pas tous les embryons qui ont survécu vont tourner pour être en santé et de sexe désiré . C'est pourquoi nous avons besoin pour gérer un protocole de traitement personnalisé établi qui permettra d'optimiser le nombre d'œufs qui seront récoltées afin que nous puissions vous offrir les meilleures chances de succès possible .



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Quelles sont mes chances de succès avec le traitement de la sélection du sexe ?

Les chances de succès dépendront d'un certain nombre de facteurs . Il s'agit notamment de votre âge , votre taux d'hormones et le niveau général de la fécondité ainsi que les caractéristiques du sperme de votre mari et d'autres facteurs tels que l'équipement utilisé , l'expérience de médecins et le choix des médicaments . Donc, il est vraiment trompeur de citer les statistiques de réussite en général ou sur la base de tout âge . Toutefois , les statistiques de l'âge sur la base que nous publions sur notre site plus ou moins donne une idée de ce que vous serez à la recherche . Cependant, votre profil hormonal individuel et vos réserves de l'ovaire sont le déterminant le plus important de la façon dont vous êtes susceptible d'atteindre le succès . Les patients jusqu'à mi-30s ont généralement une très bonne chance de tomber enceinte à la première tentative tant qu'ils ont une réserve ovarienne et un profil hormonal en fonction de leur âge . Au-dessus de l' âge de 35 ans , le niveau de baisse de la fécondité et les chances de succès de commencer à diminuer .

Dans certains cas , lorsque nous sommes en mesure d'obtenir un bon nombre et la qualité des œufs , nous finissons par avoir plusieurs embryons de sexe désiré et si il ya plus d'embryons que nécessaire pour le cycle de transfert donnée , nous sommes en mesure de préserver ceux qui seront pas être utilisés dans le cycle en cours . Cela vous donne une chance d'utiliser ces embryons conservés à une date ultérieure sans avoir à passer par l'ensemble du traitement à nouveau


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Patient Testimonial

Hi North Cyprus IVF,

Every thing was wonderful. I can't thank you enough for your support leading up to and during the treatment.

I had one boy embryo in the end so huge fingers crossed he is happy in his mummy's tummy.

I had a blood test today for my progesterone level as per my instructions. I will let you know the results as soon as I get them.

Warmest regards,

E.P, United Kingdom


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Is there anything I need to do after the embryo transfer to help become pregnant?

There will be specific guidelines handed to you after your embryo transfer. In this document, you will find information on what to do and what not to do to help the process. Once the embryo transfer has been performed, there is not much to do to assist with conception. However, there are things that can be done in order not to jeopardize the process and to make sure you don’t do things that can negatively impact embryo’s ability to implant. These have to do with your diet and physical activities that require strength. Otherwise, you will be able to continue your daily chores without any interruption, but will simply take it down a notch.

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