Hormone Testing Before Traveling to Cyprus

The first step in the IVF process would be to have the following hormone tests done on days 2-4 of the menstrual cycle, 1-2 months before you wish to proceed : 

FSH
LH
E2
Prolactin

Once the treatment begins, we will ask that you have 2 follicles tracking scans on cycle day 7 and cycle day 9.

Where can you have these done?

Spain

Marbella:  international@fivmarbella.com

Seville:  international@ginemed.es

Madrid:  info@fivcenter.com

France

Paris : Dr. Celine Davy +33 1 43 80 28 05

Germany 

Berlin : Fertility Center Berlin. Dr. Anette Siemann info@fertilitycenterberlin.de

Netherlands

Amsterdam :  info@geslachtskeuze.nl 

United Kingdom

London : The Birth Company (http://www.thebirthcompany.co.uk/) Dr. Amin Gorgy (http://www.fertility-academy.co.uk/about-us/dr-a-gorgy/)

Midlands : Cherish UK http://cherish-uk.com/

Sweden

Stockholm : Fertilitetslaboratoriet Dr. Gabor Sebestyen +46 08 585 87 504

Please do not hesitate to contact us for further information : northcyprusivfcenter@gmail.com


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Another Sweet Thank You!

Thank you so much for your email and sorry for the delay in replying my computer didn’t seem to want to send emails in Cyprus. I am now home having had my transfer on Saturday. One very good boy egg and another no quite so good put back ,so fingers crossed. Thank you so much for all your help and kindness throughout all of this. I have a progesterone test booked with my gyni this evening then I guess it’s the dreaded waiting !!

Angie was fantastic , and was great when I reacted rather badly to the anaesthetic ,not unusual  for me unfortunately.

You two make a great co-ordination team, nothing to much trouble and always there when needed and fantastic to have someone speaking English.

Thank you so much ,love

T.S - United Kingdom.

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IVF Cost in North Cyprus

Our clinic, North Cyprus Fertility and Genetics Institute was established in 1998 by Dr. Savas Ozyigit who is a pioneer in both gynecology and assisted reproduction technologies. Dr. Ozyigit has received a number of awards including Best Gyneacologist of the Year, Best IVF practice and Lifelong Achievement in Medicine.

The clinic is ISO 9001 Certified and Dr. Ozyigit is a member of the ESHRE (European Society of Human Reproduction and Embryology).

As of September 1, 2011, our clinic has officially started offering MicroSort® for sperm sorting into X (sperm that produces girls) and Y (sperm that produces boys) for Gender Selection/Family Balancing.  

We are currently offering IUI with MicroSort®, IVF with Microsort® and IVF with MicroSort® and PGD.

The treatment fees range from 2250 EUR - 7000 EUR

Please contact us for further information on our prices and packages including hotel.

Contact Details:

Email:

info@northcyprusivf.net

savas_ozyigit@yahoo.com

northcyprusivfcenter@gmail.com

Websites:

http://www.donasyon.net/

http://northcyprusivf.com/

http://www.fivaletranger.com/

Telephone:

+90 392 227 9342

+90 548 888 9855

+90 548 882 8000

+90 532 308 5578           

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Egg Retrieval and Embryo Transfer

The decision regarding the timing of the third injectable medication (Ovidrel, or HCG) is determined by a combination of events that include size and number of the leading (largest) ovarian follicles observed on ultrasound and blood level of ovarian hormone/s.  The timing of the Ovidrel/HCG injections is critically important as your egg retrieval procedure is scheduled at a specified hour following this injection.You will be provided with clear instructions regarding the timing for this injection. You must not eat or drink anything past midnight the night before the egg retrieval.Male Partners: The day your partner is instructed to take the Ovidrel or HCG injection, it is recommended that you ejaculate in order to have a fresh sample with healthier sperm available on the day of egg retrieval (unless you are instructed otherwise).

Egg Retrieval

Please note that your partner must accompany you to provide his sperm specimen at the time of your scheduled egg retrieval.  You will meet with our expert IVF nursing staff on your arrival for the scheduled egg retrieval procedure. Please feel free to mention any concerns or questions you may have before the procedure. After your paperwork is reviewed, including consents, and after all your questions are addressed, an IV will be placed in one of your arm veins for administration of medications during the egg retrieval procedure. You will then be chaperoned to our procedure room for the egg retrieval that takes approximately 30 minutes (depending on the individual patient’s ovarian response – as retrieval of eggs from a larger number of ovarian follicles may take a few extra minutes).The egg retrieval involves a transvaginal ultrasound almost identical to the scans performed during the monitoring process. We use a combination of intravenous sedatives and local anesthetic to keep you comfortable during the egg retrieval procedure. A needle guide is attached to the side of the vaginal ultrasound probe, to accommodate the egg retrieval needle; under ultrasound guidance, the needle is passed along the ultrasound guide through the wall of the vagina into the ovary and the fluid within the visible follicles is aspirated; this fluid contains the egg surrounded by cells. The aspirated fluid is passed on to the embryologist who identifies the egg from each aspirate.

Embryo Transfer Embryo transfer is a simple, painless procedure that is performed under abdominal ultrasound guidance.

When to transfer embryos:The timing of embryo transfer is dependent on the number and quality of available embryos and on individual patient related circumstances. Embryos are almost exclusively transferred on Day 3 (cleaving embryos) or Day 5 (blastocyst stage embryos).

How does one decide on the number of embryos to transfer:The decision on how many embryos to transfer is based on a number of factors including the age of the female partner, her prior reproductive history and health profile (placing in perspective risks of multiple pregnancy for the woman), the number and quality of the available embryos, and couple’s acceptability of selective reduction in the event of a high order multiple pregnancy (more than twins) resulting from embryo transfer. Couples are encouraged to discuss these considerations and communicate their concerns and preferences at any and all times through the IVF process. Your infertility specialist will review your embryo status including fertilization, embryo development and the quality of embryos on the day of embryo transfer. The embryology team and your infertility specialist will identify the most optimal of the embryos available for transfer. 

Procedure of Embryo Transfer:You will be asked to come in with a full bladder, change into a procedure gown and will be taken to the procedure room. For patients who have previously undergone an insemination, embryo transfer is a similar procedure. With you lying down, one of our trained staff members will perform an abdominal ultrasound scan (which requires a full bladder to allow optimal visualization), while your fertility specialist gently cleanses the cervix with the fluid your embryo/s are bathed in. The pre-selected embryo/s will be “loaded” into an embryo transfer catheter; the catheter is passed on to the fertility specialist who performs a trans-cervical embryo transfer under the guidance of abdominal ultrasound. For the majority, the procedure of embryo transfer takes just a few minutes. You should not feel any discomfort during the embryo transfer procedure, and will be asked to remain reclining for an additional 15 minutes.

Source : http://goo.gl/JrBjaz

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Another Pregnancy!

B & I are delighted to let you know that on Wednesday 25th Sept we welcomed our beautiful daughters Maya & Amelia into the world. They are 8 weeks early and are currently in NICU, they are well but tiny, weighing 3lbs 5oz & 3lb 11oz respectively. I will send you a picture soon.

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La cryoconservation

La cryoconservation des ovocytes
Les progrès récents dans le dans le processus de fécondation in vitro ont permis d'assurer le succès congeler , stocker et décongeler plus tard et féconder des ovules humains cryoconservés . Cryoconservation des ovocytes s'adresse à trois groupes particuliers de femmes : les personnes atteintes d' un cancer qui n'ont pas encore commencé la chimiothérapie ou la radiothérapie , et ceux en cours de traitement avec les technologies de reproduction assistée qui ne considèrent pas la congélation des embryons une option , et ceux qui voudraient préserver leur capacité future d'avoir des enfants , soit parce qu'ils ne possèdent pas encore un partenaire , ne sont pas prêts à avoir un bébé encore, mais voudrait garder cette option pour l'avenir , ou pour d'autres raisons personnelles ou médicales . Le procédé de récupération d'oeuf pour la cryoconservation d'ovocytes est la même que celle pour la fécondation in vitro . Cela inclut plusieurs semaines d' injections d'hormones et à la contraception hormonale afin de stopper l'ovulation , suivie par plus d'injections d'hormones pour stimuler les ovaires et mûrir plusieurs ovules . Quand les oeufs ont mûri , hormone supplémentaire est donné et les oeufs sont enlevés avec une aiguille guidée par échographie par voie vaginale . La procédure est réalisée sous sédation . Les œufs sont immédiatement congelés . Ovules congelés peuvent être conservés aussi longtemps que le patient souhaite , mais cela doit être indiqué avec précision , sinon , les oeufs congelés qui ne sont pas utilisées dans un délai de deux ans sont déchargées.


La cryoconservation d'embryons
La cryoconservation d'embryons ( congélation des embryons ) est la congélation des embryons «excédentaires» pour une utilisation dans des cycles de FIV ultérieures. Cette option est souvent explorée par les couples en traitement de FIV où les embryons surnuméraires qui ne seront pas transférés dans l'utérus sont congelés pour une utilisation future si la tentative de FIV échoue. Même lorsque la tentative de FIV ne manque pas et le couple est capable de concevoir , les embryons congelés peuvent être utilisés pour la seconde grossesse. Le principal avantage de l'utilisation d'embryons cryoconservés dans les futurs cycles de FIV est que la femelle n'a pas à subir une induction de l'ovulation , ce qui réduit aussi considérablement les coûts des médicaments. Les taux de réussite sont variables en fonction des caractéristiques des patients et la qualité des embryons .
Cela pourrait aussi être une option pour les couples qui ne souhaitent pas tomber enceinte tout de suite mais je voudrais préparer leurs embryons à l'avance pour une utilisation future . De cette façon , ils peuvent éviter des taux de réussite inférieurs de conception à un âge avancé .

Cryoconservation du sperme
La congélation du sperme ( cryopréservation ) est une méthode utilisée pour les patients masculins qui suivent un traitement de chimiothérapie pour un cancer ou de maladies similaires . Cela permet au patient de conserver leur sperme pour une utilisation future et éviter les risques d'infertilité associés à la chimiothérapie .


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Treatment Plan for IVF with PGD

Below is a typical treatment plan for IVF with PGD.

The dosage and medication is subject to individual hormone results and age.

Please contact us for further information - http://goo.gl/vUjGcY

Date	Use of Medication	Additional Notes
Day 1 of Menstrual Period	Start taking 1 tablet of Pregnacare every day.	Please inform us
Day 2 of Menstrual Period	1) Femara tablets (one in the morning)
Day 3 of Menstrual Period	1) Femara tablets (one in the morning) 2) Gonal-F 300 i.u. in the morning. 3) Menopur 150 i.u. at night.
Day 4 of Menstrual Period	1) Femara tablets (one in the morning) 2) Gonal-F 300 i.u. in the morning. 3) Menopur 150 i.u. at night.
Day 5 of Menstrual Period	1) Femara tablets (one in the morning) 2) Gonal-F 300 i.u. in the morning. 3) Menopur 150 i.u. at night.
Day 6 of Menstrual Period	1) Femara tablets (one in the morning) 2) Gonal-F 300 i.u. in the morning. 3) Menopur 150 i.u. at night.
Day 7 of Menstrual Period	1)Gonal-F 300 i.u. in the morning. 2) Menopur 150i.u. at night.	First sonogram day. You will need to see your gynecologist for follicle tracking. We will need to know how many follicles exist in each ovary and what their sizes are.
Day 8 of Menstrual Period	1) Gonal-F 300 i.u. in the morning. 2) Menopur 150 i.u. at night.
Day 9 of Menstrual Period	1) Gonal-F 300i.u. in the morning. 2) Menopur 150 i.u. at night. 3) Cetrotide 0.25 mg injection (1 hour after Menopur injection)	Second sonogram day. You will need to see your gynecologist for follicle tracking. We will need to know how many follicles exist in each ovary and what their sizes are. You are more than likely to start using cetrotide today, based on the scan results.
Day 10 of Menstrual Period	1) Gonal-F 300 i.u. in the morning. 2) Menopur 150 i.u. at night. 3) Cetrotide 0.25 mg injection (1 hour after Menopur injection)
Day 11 of Menstrual Period	1) Gonal-F 300 i.u. in the morning. 2) Menopur 150 i.u. at night. 3) Cetrotide 0.25 mg injection (1 hour after Menopur injection)	You should refrain from all sexual activity from this point onward.
Day 12 of Menstrual Period	1) Gonal-F 300 i.u. in the morning. 2) Menopur 150 i.u. at night. 3) Cetrotide 0.25 mg injection (1 hour after Menopur injection)	Arrival in Cyprus.
Day 13 of Menstrual Period		Third sonogram. You are likey to have your trigger injection done later on in the day. You will spend about 3 hours at the clinic, until 1 PM.
Day 14 of Menstrual Period		Enjoy Cyprus!
Day 15 of Menstrual Period	1) Crinone gel 8% applied one in the morning and one at night.	Expected day of your egg retrieval. Your husband will provide his sample today. Nurses will explain how the crinone gel will be used. You will spend about 4 hours at the clinic in the morning (9.30 AM – 130 PM)
Day 16 of Menstrual Period	1) Crinone gel 8% applied one in the morning and one at night.
Day 17 of Menstrual Period	1) Crinone gel 8% applied one in the morning and one at night.
Day 18 of Menstrual Period	1) Crinone gel 8% applied one in the morning and one at night.
Day 19 of Menstrual Period	1) Crinone gel 8% applied one in the morning and one at night.
Day 20 of Menstrual Period	1) Crinone gel 8% applied one in the morning and one at night.	This is the expected day of embryo transfer. You will start using aspirin tablets immediately after the embryo transfer. You will spend about 3-4 hours at the clinic in the morning.

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Testimonial from Switzerland

We went to North Cyprus IVF in February 2013 . I am menopaused. The miracle happened: I got pregnat but unfortunalty only for 1 month: miscarriage. We want to say thank you to Amy for her efficiency. We have been impressed by the professionalism, the efficiency and the kindness of everybody at North Cyprus IVF! At each step of the process, everything was clearly explained and all our requests, questions have been answered. From the bottom of our heart big thanks to Mrs. Angie Ali, Dr. Savas Ozyigit, Dr. Idil Aslan and all the staff included Mr. Niasi, the driver. We recomend the clinic for its professionalism and compassionate environment. For the accomodation, we suggest the Golden Tulip hotel very close to the clinic.

ALI, Switzerland

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Fertility Drugs

An IVF Medication cycle consists of different medications or fertility drugs that stimulate the body to promote pregnancy using IVF. The particulars of the cycle are decided by a specialist physician, below are some of the most widely used medications.

GnRH Agonists - Allow for improved control of ovarian stimulation during the administration of exogenous FSH. Exogenous FSH is given to stimulate ovarian follicle, followed by human chorionic gonadotropins (hCG) to trigger ovulation. Some GnRH agonists are: Buserelin, Leuprorelin, Nafarelin, Lupron (Prostap), Triptorelin, Decapeptyl and Synarel. Some are injected just under the skin others are applied as a nasal spray. They allow the body to produce a higher number of improved quality eggs during the treatment cycle. Midcycle hormonal surge caused by a cancellation of a cycle can also be minimised using these.

Antagonists - Cetrotide, Ganirelix and Antagon are IVF medications that are given by injection usually for three or four days they are antagonists of gonadotropin releasing hormones (GnRH) and are used to prevent premature ovulation.

Gonadotropin preparations - are medications that simulate the physiological effects of gonadotropins. They are taken as subcutaneous injections that provide stimulation to the follicles that contain the eggs during the stimulation phase. Gonal F, Menopur, Merional, Fostimon, Puregon, Bravelle, Follistim, Pergonal and Repronex are the most commonly used gonadotropins.

Human Chorionic Gonadotrophin (hCG) - The administration of hCG in the presence of one or more mature ovarian follicles can trigger ovulation to aid egg retrievel and it can also be used to stimulate the production of progesterone. The most commonly used hCGs are Pregnyl, Ovitrelle, Profasi and Novarel.

Prednisolone / Medrol - Generic name is Methylprednisolone and is a cortisteroid based hormone. It is normally given for a period of four days during the IVF cycle, to assist pre-embryo implantation.

Doxycycline - an antibiotic also know by the brand names Vibramycin, Monodox, Microdox, Periostat, Vibra-Tabs, Oracea, Doryx, Vibrox, Adoxa, Doxyhexal, Doxylin, Doxoral and Atridox. It is administered in pill form and is given to the male partner during the wife's stimulation IVF cycle to reduce the minute levels of bacteria found in the semen. This bacteria can compromise the performance and quality of the sperm during an IVF cycle. It is also sometimes given to the female to reduce the risk of infection following aspiration of the follicles during the egg retrieval period.

Progesterone - Natural Progesterone can be taken as a daily intramuscular injection called Gestone, starting two days after egg retrieval and continuing until the placenta is making adequate amounts of Progesterone. It can be given in the form of a pessary or suppository called Cyclogest. It is given in the dose of 400 mg twice daily rectally until embryo transfer and rectally or vaginally after embryo transfer. Progesterone can also be given in the form of a vaginal gel Crinone or Capsules called Utrogestan. It is essential to prepare the endometrium for implantation of an embryo, ovulation induction or sometimes to induce a period in a woman who hasn't ovulated.

Source - http://goo.gl/ICugOW

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Frequently Asked Questions

Is it legal to choose baby's sex?

Yes, as North Cyprus IVF clinic, we are able to offer gender selection IVF in line with the North Cyrus legal system. Even though gender selection is not allowed in most parts of Europe, having gender selection IVF treatment in North Cyprus is completely legal.

Is gender selection possible without IVF?

Yes, At North Cyprus IVF we are able to offer microsort with IUI (artificial insemination). Microsorting technologies allow for gender selection through IUI treatment. However, microsort is only about 75% accurate for a male child and about 90% accurate for a female child, therefore, combining microsort with PGD always results in a more accurate gender selection method.

Is there a 100% guarantee for success with gender selection IVF?

Even though there is no such thing as 100% in real-life sciences, we quote a 99% chance for accurate sex selection through PGD.

Can I use PGD for genetic screening?

Absolutely! PGD is not only for gender selection. With PGD testing, we can also screen for major genetic disorders associated with chromosomes X, Y, 13, 18 and 21 which are the causes of about 85% of all major genetic disorders.

Can I select the sex of my first child?

Even though at North Cyprus IVF, we recommend that gender selection is only performed for family balancing for second or third child, selecting the sex of your first child is also possible if you believe this is an appropriate family balancing act.

Do I still use medication for gender selection IVF even if I have no fertility problems?

Even if you have no fertility issues and you are able to conceive naturally, we will still need to put you on stimulation medication on order to obtain multiple eggs in the ovaries. This will allow us to fertilize multiple eggs, and perform the necessary genetic testing on them to identify the healthy embryos that are of appropriate sex for the embryo transfer.

What happens to the embryos that are unused?

You have the choice of freezing any unused embryos for future use. If you wish not to freeze them, the embryos are disposed.

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Another Sweet Review

Dear North Cyprus IVF, 

Couldn't wait another 2 weeks to see my beautiful baby. So had a cheeky scan she is healthy with a perfect heartbeat and the boys loved seeing her! She was waving and kicking her legs. 

Thank you so much for giving me my baby girl.

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Thank you North Cyprus IVF

Thank you for everything! You guys did a great job! We are so grateful.

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Quick Note

Hi,

I am extremely pleased overwhelmed ecstatic to inform you I am pregnant. I had my blood tests today and I was 54. They have faxed over the results to your clinic so you've probably already seen them. They only just called me to let me know.

Thanks Again for all your support 

With love

B. L., United Kingdom

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Another Lovely Review!

Dear North Cyprus IVF Team,

So sorry this email has taken so long to write but we have been

busy!!

We came to see you in May 2012 for treatment and we did

let you know after our test that we were expecting twins We are

delighted to tell you that on 20/12/12 Elouise and Ethan were born.

They arrived seven weeks early and were in the special care unit for

seven weeks. Elouise was born at 4lb 6oz and Ethan was 3lb.

Both had a few initial health issues but we are pleased to say that all

have been resolved. They are now 14lb 12oz and 15lb 5oz respectively!

What can we say!! Words are not enough but please say a massive

thankyou to the whole team led by Dr Savas and Dr Idil. We will be

eternally grateful to you all. You are all amazing.

We have attached one photo that includes us to jog your memory as you

must see so many people. There is one when the twins were first born

and another more recent one.

Wishing you all peace and happiness.

THANK YOU

P and T, S (United Kingdom) 

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Fertility Scans

Fertility Scans

Many couples who are having Fertility Treatment abroad, or at a location some distance from their own home within the UK, want the facility to access an ultrasound scan on a particular day of the menstrual cycle.

Cherish-UK is able to perform the specialist scan and email the result to the chosen clinic. This allows more flexibility for couples and reduces the amount of time spent away from home during the treatment cycle.

Usually clinics request a scan to assess antral follicle count and or a scan to assess endometrial thickness andfollicular development.

During your scan we will explain the findings to you and following your scan we will give you your images and email the report to you. We will email your report to your chosen clinic and if requested we will scan your images and also send them to the clinic.

Why is endometrial thickness important?

During a natural and stimulated cycle, it is important to assess the thickness of the endometrium (womb lining). Endometrial thickness needs to be 7mm or above for a pregnancy to be able to implant.

What is Anti-Mullerian Hormone?

This is a hormone blood test, which provides information regarding ‘ovarian reserve’. This is a term, which is used to reflect the size of the pool of eggs left within the ovary and gives an indication of the likelihood of success during a stimulated cycle. Anti-Mullerian Hormone (AMH) test can be done on any day of the woman’s cycle. Cherish-UK can organise this blood test if required.

How do I book fertility ultrasound scans?

Cherish-UK is a private pregnancy and fertility scanning clinic, you can self refer and arrange an appointment at your convenience. To book fertility ultrasound scans please telephone us on: 07580 611 879, fill out our online enquiry formor email us at info@cherish-uk.com.

Do I need to prepare for my fertility ultrasound scan?

For a fertility ultrasound scan we recommend that you arrive with a full bladder and drink a litre of fluid prior to your appointment. This will improve the quality and aid visibility of the ultrasound scan.

What's included in your fertility ultrasound scan?

Our fertility ultrasound scan fees cover all aspects of your appointment which will include the following:

• Full Consultation
• Transabdominal Ultrasound Scan and/or Transvaginal Ultrasound Scan
• Black and White Ultrasound Scan Image(s)
• Ultrasound Scan Report
• Folder which is suitable for storing information
• Display card for ultrasound images

Source : Cherish UK http://goo.gl/XQT7V

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Requirements and Recommendations for Microsort

http://

MicroSort is available for couples who are looking to balance their families or prevent certain genetic diseases.

What are the requirements for family balancing?
Couples who want to use MicroSort to balance the genders of their children must:

• Have at least one child
• Sort for the underrepresented gender in the family
• Be negative for HIV, and Hepatitis B surface antigen and C antibody

What are the requirements for couples at risk for X-linked disorders?
Couples who want to use MicroSort to reduce the probability of genetic disease transmission must:

• Be a known carrier of an X-linked or X-limited disorder
• Be negative for HIV, and Hepatitis B surface antigen and C antibody

MicroSort laboratories are not equipped to process infectious samples; therefore all patients must present negative testing results for the following:

• HIV I and II
• Hepatitis B and C*
• VDRL

The mentioned testing can be performed in any certified lab as long as they were performed no more than six months prior to the date of the procedure.

The MicroSort procedure is a demanding process requiring a high number of motile sperm be provided for sorting so that sufficient viable sperm are sorted for use in assisted reproductive techniques. We strongly recommend you provide the results of a semen analysis performed as close as possible to the date of your procedure. These results will provide the semen characteristics that our staff can use to estimate the expected results and plan for any different measures that can be considered based on your semen analysis.

While semen analysis is not a requirement of MicroSort, if your procedure is canceled due to too few viable sperm, there will be a cancellation fee of 40% of the total cost of the procedure.

For best semen quality results, MicroSort recommends:

• Abstinence for two or three days.
• No alcohol consumption during that period.
• No exposure to high temperatures, such as hot water, hot tubs, vapor rooms, etc.

*Patients that have received hepatitis vaccines should get the appropriate tests to avoid false positives.

Source : Microsort® bit.ly/12Arr1e




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