An IVF Medication cycle consists of different medications or fertility drugs that stimulate the body to promote pregnancy using IVF. The particulars of the cycle are decided by a specialist physician, below are some of the most widely used medications.
GnRH Agonists - Allow for improved control of ovarian stimulation during the administration of exogenous FSH. Exogenous FSH is given to stimulate ovarian follicle, followed by human chorionic gonadotropins (hCG) to trigger ovulation. Some GnRH agonists are: Buserelin, Leuprorelin, Nafarelin, Lupron (Prostap), Triptorelin, Decapeptyl and Synarel. Some are injected just under the skin others are applied as a nasal spray. They allow the body to produce a higher number of improved quality eggs during the treatment cycle. Midcycle hormonal surge caused by a cancellation of a cycle can also be minimised using these.
Antagonists - Cetrotide, Ganirelix and Antagon are IVF medications that are given by injection usually for three or four days they are antagonists of gonadotropin releasing hormones (GnRH) and are used to prevent premature ovulation.
Gonadotropin preparations - are medications that simulate the physiological effects of gonadotropins. They are taken as subcutaneous injections that provide stimulation to the follicles that contain the eggs during the stimulation phase. Gonal F, Menopur, Merional, Fostimon, Puregon, Bravelle, Follistim, Pergonal and Repronex are the most commonly used gonadotropins.
Human Chorionic Gonadotrophin (hCG) - The administration of hCG in the presence of one or more mature ovarian follicles can trigger ovulation to aid egg retrievel and it can also be used to stimulate the production of progesterone. The most commonly used hCGs are Pregnyl, Ovitrelle, Profasi and Novarel.
Prednisolone / Medrol - Generic name is Methylprednisolone and is a cortisteroid based hormone. It is normally given for a period of four days during the IVF cycle, to assist pre-embryo implantation.
Doxycycline - an antibiotic also know by the brand names Vibramycin, Monodox, Microdox, Periostat, Vibra-Tabs, Oracea, Doryx, Vibrox, Adoxa, Doxyhexal, Doxylin, Doxoral and Atridox. It is administered in pill form and is given to the male partner during the wife's stimulation IVF cycle to reduce the minute levels of bacteria found in the semen. This bacteria can compromise the performance and quality of the sperm during an IVF cycle. It is also sometimes given to the female to reduce the risk of infection following aspiration of the follicles during the egg retrieval period.
Progesterone - Natural Progesterone can be taken as a daily intramuscular injection called Gestone, starting two days after egg retrieval and continuing until the placenta is making adequate amounts of Progesterone. It can be given in the form of a pessary or suppository called Cyclogest. It is given in the dose of 400 mg twice daily rectally until embryo transfer and rectally or vaginally after embryo transfer. Progesterone can also be given in the form of a vaginal gel Crinone or Capsules called Utrogestan. It is essential to prepare the endometrium for implantation of an embryo, ovulation induction or sometimes to induce a period in a woman who hasn't ovulated.
Source - http://goo.gl/ICugOWGnRH Agonists - Allow for improved control of ovarian stimulation during the administration of exogenous FSH. Exogenous FSH is given to stimulate ovarian follicle, followed by human chorionic gonadotropins (hCG) to trigger ovulation. Some GnRH agonists are: Buserelin, Leuprorelin, Nafarelin, Lupron (Prostap), Triptorelin, Decapeptyl and Synarel. Some are injected just under the skin others are applied as a nasal spray. They allow the body to produce a higher number of improved quality eggs during the treatment cycle. Midcycle hormonal surge caused by a cancellation of a cycle can also be minimised using these.
Antagonists - Cetrotide, Ganirelix and Antagon are IVF medications that are given by injection usually for three or four days they are antagonists of gonadotropin releasing hormones (GnRH) and are used to prevent premature ovulation.
Gonadotropin preparations - are medications that simulate the physiological effects of gonadotropins. They are taken as subcutaneous injections that provide stimulation to the follicles that contain the eggs during the stimulation phase. Gonal F, Menopur, Merional, Fostimon, Puregon, Bravelle, Follistim, Pergonal and Repronex are the most commonly used gonadotropins.
Human Chorionic Gonadotrophin (hCG) - The administration of hCG in the presence of one or more mature ovarian follicles can trigger ovulation to aid egg retrievel and it can also be used to stimulate the production of progesterone. The most commonly used hCGs are Pregnyl, Ovitrelle, Profasi and Novarel.
Prednisolone / Medrol - Generic name is Methylprednisolone and is a cortisteroid based hormone. It is normally given for a period of four days during the IVF cycle, to assist pre-embryo implantation.
Doxycycline - an antibiotic also know by the brand names Vibramycin, Monodox, Microdox, Periostat, Vibra-Tabs, Oracea, Doryx, Vibrox, Adoxa, Doxyhexal, Doxylin, Doxoral and Atridox. It is administered in pill form and is given to the male partner during the wife's stimulation IVF cycle to reduce the minute levels of bacteria found in the semen. This bacteria can compromise the performance and quality of the sperm during an IVF cycle. It is also sometimes given to the female to reduce the risk of infection following aspiration of the follicles during the egg retrieval period.
Progesterone - Natural Progesterone can be taken as a daily intramuscular injection called Gestone, starting two days after egg retrieval and continuing until the placenta is making adequate amounts of Progesterone. It can be given in the form of a pessary or suppository called Cyclogest. It is given in the dose of 400 mg twice daily rectally until embryo transfer and rectally or vaginally after embryo transfer. Progesterone can also be given in the form of a vaginal gel Crinone or Capsules called Utrogestan. It is essential to prepare the endometrium for implantation of an embryo, ovulation induction or sometimes to induce a period in a woman who hasn't ovulated.
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